Hair loss is a possible side effect for patients in chemotherapy or radiation treatment for cancer. However, not all therapies cause hair loss. According to the National Cancer Institute (NCI), alopecia from chemotherapy is usually reversible. There are a wide range of options for managing hair loss, how to cope emotionally, and how to approach aftercare when your hair resumes growth. For those experiencing hair loss and the complex emotions that accompany it, you are not alone. To help ease patients through this transition, the Hirshberg Foundation is sharing some important resources to address this side effect. We also encourage you to share your concerns with your healthcare team to determine the best choice for you.

As the Hirshberg Foundation brings our vibrant community of supporters and fundraisers together for the 26th LA Cancer Challenge, we are thrilled to share that this year’s Honorary Starter will be 21-year pancreatic cancer survivor, Roberta Luna!

For two decades, Roberta and her beloved husband Vic have been on a crusade to give back to their community and to embrace patients and caregivers going through a journey that the Lunas know all too well. “Through my experience with this horrific disease, I believe I am here to help those who have also been affected by pancreatic cancer, to hopefully inspire them and give them much needed hope.” Putting her beliefs into action, Roberta is a volunteer, activist, patient advocate, guest speaker at awareness events and survivor panelist at the Hirshberg Foundation’s Symposium for Pancreatic Cancer. This year we are thrilled to welcome her as our LACC Honorary Starter, and we invite you to register and join us too!

Over the years, Roberta has shared her harrowing story of how pancreatic cancer took her father, her mother and her uncle before impacting her own personal health by her early 40’s. “I decided then and there I wasn’t going to die; I was going to fight this with everything I had.” Every step of the way, Roberta has stood strong as an advocate for patients. Most recently, she has given a voice to fellow survivors through her podcast: Living Hope; Your Journey with Pancreatic Cancer. Living Hope is a weekly podcast sharing the real-life journeys of those affected by this disease. Her goal is to educate, raise awareness, provide hope, and a spark of inspiration for survivors and caregivers. The Living Hope podcast is also a returning sponsor of the LA Cancer Challenge this year.

Today, Roberta instills hope in newly diagnosed patients and long-term survivors alike. “Hopefully, you find inspiration from my story about how, through the good, the bad and the ugly, we can weather the storm with the support of our loved ones, our family, ‘our purple family’ and the many people we meet along this often-difficult journey.”

We are honored and humbled to call her a friend of the Foundation. As the Hirshberg Foundation shares its LACC mantra to “Fight to the Finish,” there are no better words than a quote Roberta shared years ago. “As I lace up my purple boxing gloves for the 19th time, I challenge pancreatic cancer to put on its gloves and prepare for the next round…I am still standing and I’m not giving up!”

Summer is in full swing, and we have research updates to share plus great ways to get involved in making a difference for the pancreatic cancer community. Our events continue to unite a community passionate about a cancer-free future and ensure that we can continue to fund research that drives us towards that goal. As our 25th year concludes, we remain steadfast in offering hope with the motto, “Never Give Up! Finding a cure is worth fighting for.” 

Dr. Timothy Donahue, Director of the UCLA Agi Hirshberg Center for Pancreatic Diseases and Garry Shandling Chair in Pancreatic Surgery at David Geffen School of Medicine at UCLA, has joined the Pancreatic Cancer Early Detection (PRECEDE) Consortium as a Principal Investigator. This Consortium brings together an international, multi-institutional collaborative group of experts with the aim to increase the 5-year survival rate from 10% to 50% in the next 10 years. With Dr. Donahue as a Principal Investigator, UCLA patients with a family history of pancreatic cancer or individuals who carry pathogenic genes will be able to enroll in the PRECEDE study for longitudinal follow up.

The PRECEDE Study is an observational long-term study of people with an increased risk for pancreatic cancer due to family history, a history of chronic pancreatitis or pancreatic cysts, or the presence of specific gene mutations linked to the disease. Study participants have blood work every 6 to 12 months with additional imaging collected for those in defined high-risk groups. This data-driven model integrates basic, translational and clinical research to greatly enhance our understanding of this disease and to drive early detection and prevention methods. The consortium aims to identify high-risk individuals, create an effective early detection test for pancreatic cancer, understand the risk factors, including susceptible genes, and develop a strategic pancreatic cancer prevention plan. As Dr. Donahue told us, “It is critical for high-risk individuals to join this important study in order to maximize identification and advance early detection of pancreatic cancer. Early detection would drastically change the trajectory of the disease and ultimately save thousands of lives.”

The Agi Hirshberg Center for Pancreatic Diseases and UCLA’s involvement in this study will expand the population of high-risk individuals involved and allow family members of patients to participate in deepening our knowledge of pancreatic cancer risk factors. We are hopeful that this collaborative, multi-institution project will make early detection and prevention for pancreatic cancer accessible for all so that we may see a marked increase in survival rates.

The National Comprehensive Cancer Network (NCCN) works to improve cancer care through their vast collection of Guidelines for Patients. The latest version of the Guidelines for Patients: Pancreatic Cancer, sponsored by the Hirshberg Foundation, provides information to help patients and their families navigate a pancreatic cancer diagnosis in an empowered and informed way.

The extensive guidelines include care options, treatment protocols, quotes from patients, advice for how to discuss treatment with doctors, and much more. The Guidelines for Patients are based on the recommendations in the NCCN Clinical Practice Guidelines in Oncology available to physicians. One of the most recent updates included for patients is the addition of a new first-line therapeutic option, liposomal irinotecan + 5-FU + leucovorin + oxaliplatin (known as NALIRIFOX). This new drug regime has shown promise in early-stage trials conducted by Dr. Zev Wainberg, a member of the UCLA Agi Hirshberg Center for Pancreatic Diseases, Professor of Medicine at UCLA and co-director of the UCLA GI Oncology Program.

Another highlight of the updated version is the recommendation that all individuals diagnosed with pancreatic cancer have genetic testing for a range of inherited mutations. The advice is to screen beyond just BRCA1 and BRCA2 to look at an array of mutations that can assist with treatment planning. There is also an expanded section on biomarker profiling for advanced and metastatic pancreatic cancer which can provide a molecular profile of small yet important features of the cancer. Biomarkers detect abnormal changes in cancer cells’ genes that occurred during your lifetime and may also help with treatment planning.

An update that we are excited to focus on is the whole-body approach to treatment that is emphasized in the latest Patient Guidelines. The Hirshberg Foundation has long advocated for a holistic method of treatment that takes into consideration the mind-body connection. The newest updates include details on supportive care that is recommended from the point of diagnosis. Treatment options have also taken on the best-practice of a more individualized approach based on individual and cancer specific characteristics.

The Hirshberg Foundation is proud to support this great work to ensure that all patients and caregivers receive the most up-to-date information to assist them through their cancer journey. The NCCN Guidelines for Patients booklet is available for digital download or to purchase through Amazon.